1. In spite of their poverty, they are very generous.
→ Though they are poor, they are very generous.
2. Even though he usually tells lies, many people believe him.
→ Despite the fact that he usually tells lies, many people believe him.
3. Although Lan is a poor student, she studies very well.
→ Despite being a poor student, Lan studies very well.
4. Despite trying many times, she hasn’t given up.
→ Although she has tried many times, she hasn’t given up.
5. Although she was out of money, she went shopping.
→ Despite being out of money, she went shopping.